Hepatotoxicity after Desflurane Anesthesia in a 15-month-old Child with Mobius Syndrome after Previous Exposure to Isoflurane

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Hepatotoxicity after desflurane anesthesia in a 15-month-old child with Mobius syndrome after previous exposure to isoflurane.

HALOGENATED anesthetic agents have been associated with perioperative liver dysfunction and injury. Most cases of hepatotoxicity reported involve halothane exposure. Halothane produces two types of hepatotoxicity. A mild, transient syndrome with modest increases in transaminase enzymes occurs in 20% of patients given halothane. A more severe and fulminant hepatitis with marked liver dysfunction...

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ژورنال

عنوان ژورنال: Anesthesiology

سال: 2007

ISSN: 0003-3022

DOI: 10.1097/01.anes.0000287196.15665.16